Mushrooms rich in beta-glucans have traditionally been used in the medical practices of various cultures, including traditional Chinese, Japanese, and Korean medicine.

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The substances in mushrooms are essential for the human body, providing energy, improving digestion, regulating blood sugar levels, normalizing cholesterol, and exhibiting immunomodulating properties. Regular consumption of mushrooms or their extracts can significantly enhance overall health.

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Polysaccharides: Natural Multifunctional Carbohydrates

Polysaccharides are natural high-molecular-weight carbohydrates with a wide range of therapeutic effects. Special attention is given to beta-glucans, an essential component of dietary fiber with strong immunostimulatory, anti-inflammatory, and antioxidant properties.

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How Polysaccharides and Polysaccharide Peptides Work

Polysaccharides, which are complexes of glucose molecules, are metabolized slowly, providing sustained energy, improving digestion, and offering immunomodulatory benefits. Due to their complex structure, glucose remains in the extracellular environment until insulin facilitates its entry into cells, enabling energy reserves to be replenished.

Polysaccharide peptides are integrated into a complex polysaccharide matrix. The polysaccharides help deliver these peptides to immune system cells. Acting like a locomotive, the polysaccharides "pull" the peptides toward the cells. Once inside, the peptides nourish immune cells, such as T-cells, macrophages, natural killer (NK) cells, neutrophils, monocytes, and interferons, while also stimulating B-lymphocytes responsible for antibody production. This process strengthens the immune system and enhances the body's ability to combat atypical cells, bacteria, viruses, and debris from damaged cells.

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Beta-Glucans: The Key Therapeutic Component

Beta-glucans found in mushrooms form the foundation of their therapeutic effects.

Immunostimulation

• Activates macrophages, NK cells, and dendritic cells via Dectin-1 and TLR-2/4 receptors.

• Stimulates the production of interleukins (IL-6, IL-12) and other cytokines, strengthening both innate and adaptive immunity.

• Enhances protection against viral, bacterial, and fungal infections.

Antitumor Effects

• Activates immune cells that identify and destroy cancer cells.

• Inhibits tumor growth by reducing angiogenesis (the formation of new blood vessels that nourish tumors).

Anti-inflammatory Effects

• Modulates inflammatory cytokine activity and reduces inflammatory pathways, such as NF-κB.

• Beneficial for autoimmune and chronic inflammatory conditions.

Antioxidant Properties

• Reduces oxidative stress, protecting cells from damage.

• Neutralizes free radicals and helps prevent premature aging.

Gut Microbiota Support

• Promotes the growth of beneficial microorganisms in the gut, strengthening barrier functions and improving digestion.

Cardioprotective Effects

• Protects blood vessels from damage by reducing inflammation and oxidative stress.

• Improves blood lipid profiles, although this effect is stronger with beta-glucans derived from grains.

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Natural Peptide-Polysaccharide Complexes

Based on extracts from medicinal mushrooms containing polysaccharide peptides (PSP), polysaccharides, and beta-glucans, the "My Real Way" series of natural peptide-polysaccharide complexes has been developed to strengthen the immune system and provide antitumor protection.

These complexes are used as an adjunct therapy for oncology patients undergoing chemotherapy or radiation therapy to reduce symptoms such as fatigue, appetite loss, nausea, vomiting, and pain. To enhance therapeutic effects, it is recommended to combine peptide-polysaccharide complexes with multi-component peptide bioregulators from the "My Real Way" series, targeting specific organs.